CE MDR Class IIb Certified · ISO 13485 · Published in The Lancet

Revolutionizing Lung Health with AI Support.

Nexus AI CXR is a CE MDR Class IIb certified medical device that analyses chest X-rays and indicates findings not consistent with a normal lung field, including patterns suggestive of pulmonary tuberculosis. It supports and does not replace clinical interpretation and diagnosis.

CE MDR Class IIb marking – Nexus AI CXR certified medical device
CE MDR Class IIbCertified SaMD
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The LancetDigital Health · 2024
Google
GoogleDevelopment Partner
ISO
ISO 13485:2016Quality Certified
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Published in The Lancet. Powered by Google. Trusted by clients.

Nexus AI · Live analysis STUDY-0000000027
Chest X-ray with Nexus AI heatmap visualisation for TB and lung pathology detection
CE MDR Class IIb · Certified output
<45 sec
Analysis time per chest X-ray
From upload to AI findings
0+
Chest X-rays in initial training data
Across 10 countries · Multi-region datasets
0+
In-kind screenings delivered
Nexus × Google social impact drive
Trusted by partners across global lung health
The Global Fund Stop TB Partnership FIND – Diagnosis for all World Vision Department of Health, Republic of South Africa Ministère de la Santé, Côte d'Ivoire Ministry of Health, Sierra Leone Ministère de la Santé, DRC Advance Access & Delivery Scholtz Partners Diagnostic Radiologists SIOC Community Development Trust The Aurum Institute PFSCM Google Health – development partner for Nexus AI CXR chest X-ray AI
The platform
The Nexus AI workspace
Nexus AI CXR study view with FIR and TB Suggestive AI annotations on chest X-ray
The platform

Nexus AI Platform.

Simple. Understandable. Built for real clinical environments.

An integrated enterprise AI platform supporting population screening, radiology workflows, and occupational lung health programmes – developed for flexible deployment across diverse clinical environments.

Designed to support trained healthcare professionals.
Clinical judgement always remains with the clinician.
  • Cloud or on-premises · Online or offline
  • DICOM, JPEG, and PNG inputs with automated quality verification
  • Real-time AI findings with isolines, heatmaps, and confidence scores
  • LLM-powered clinical insights and structured reports (Beta)
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Simple
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Understandable
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Built for real clinical environments
Developed in collaboration with Google Health – development partner for Nexus AI CXR chest X-ray AI
Our approach

Our approach to integrated lung health.

Nexus is a connected platform that brings together our CE-certified medical device for chest X-ray screenings, multi-pathology, and LLM capabilities, integrated within a broader lung health ecosystem – optimising workflows and delivering faster, more coordinated screening outcomes.

CE MDR Class IIb

Nexus AI CXR

A CE-certified medical device that analyses chest X-rays and indicates findings not consistent with a normal lung field, including patterns suggestive of pulmonary tuberculosis. The algorithm comprises two core models – Normal and TB – that run in parallel on every chest X-ray.

  • • Normal model – flags findings as FIR
  • • TB model – classifies as TB Suggestive (with score)
  • • Isolines & heatmaps for every finding
  • • Validated as published in The Lancet
Explore the certified product →
Beta version

Multi-Pathology AI + LLM

Builds on the CE-certified Nexus AI CXR and adds an extra layer of classification – assigning descriptive labels to certain radiological findings, plus LLM-assisted clinical insights and structured reporting. Internally validated. We are currently in the process to expand our CE certification.

  • • Descriptive labels for radiological findings
  • • Silicosis – validated by Stop TB
  • • LLM-assisted clinical insights & structured reporting
See what's next in Beta →
Integrated ecosystem

Comprehensive Lung Health Ecosystem

Nexus AI CXR is integrated with Healthcare Framework (clinical management) and CloudX (central radiology reporting) to deliver coordinated screening – from a single chest X-ray to a complete patient pathway. Holistic approach for optimal outcomes.

  • • Nexus AI CXR – Screening engine
  • • Healthcare Framework – Clinical management
  • • CloudX – Central radiology reporting
  • • Coordinated, end-to-end workflow
Explore the ecosystem →
Evidence & performance

Validated where it matters: in the field, by independent bodies, in peer-reviewed literature.

The Lancet Digital Health – Nexus AI CXR CAD performance comparison against WHO TB screening thresholds
Independent CAD AI benchmark · Published in The Lancet Digital Health

Nexus AI CXR was developed on over 460,000 chest X-rays from 10 countries across diverse populations and imaging modalities, and has been independently validated by both Nexus and Google. Both the Normal model and the TB model met or exceeded the World Health Organization's performance thresholds (≥90% sensitivity, ≥70% specificity).

Nexus AI CXR was further independently validated by the Stop TB Partnership and ranked as one of the top two performing models as published in The Lancet – confirmed across HIV-positive, female, male, and age subgroups.

Nexus continues to refine our models through ongoing post-market surveillance and additional training – a commitment to continuous improvement in real-world clinical performance.

Read the publication →
Real-world impact

Real-world impact, proven in the field.

From mobile screening clinics in rural Africa to deep-shaft mining sites in South Africa, Nexus AI is supporting lung health across diverse healthcare environments.

Global Impact & Case Studies
APR 02, 2026

Nexus Intelligence redefines the boundaries of medical diagnostics with world-first AI deployment 4 km underground

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Global Impact & Case Studies
JAN 17, 2026

Real-world impact: screening the underserved at scale

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Industry Insights
SEP 24, 2025

Beyond imaging: integrating LLMs into the radiology workflow

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Clinical Innovation
SEP 24, 2025

The new standard in lung health: Nexus AI achieves CE MDR Class IIb certification

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Ready to see Nexus AI in your workflow?

Book a 30-minute platform walkthrough with our clinical team. We'll show you live AI analysis, integration options, and walk you through deployment in your environment.

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Decision-support tool. Nexus AI CXR 1.0 is a CE MDR Class IIb certified medical device intended to assist qualified healthcare professionals. It does not replace diagnostic interpretation by a trained clinician. All outputs must be interpreted in conjunction with the patient's clinical context, medical history, and additional diagnostic results. Multi-pathology classification (lung cancer, silicosis, nodules, fibrosis and others) is available as a Beta feature and is not part of the CE MDR Class IIb certification.